将红色和黑色甘草棒，彩色棉花糖或软糖熊，牙签，针，绳子和剪刀聚集在一起。为有色棉花糖或芋头熊指定名称以代表核苷酸碱基。应该有四种不同的颜色，每种颜色代表腺嘌呤，胞嘧啶，鸟嘌呤或胸腺嘧啶。为彩色甘草片指定名称，一种颜色代表戊糖分子，另一种代表磷酸分子。用剪刀将甘草切成1英寸的块。使用针头，将一半的甘草片一起在黑色和红色片之间纵向交替。
对剩余的甘草块重复该过程，以创建总共两个相等长度的林分。使用牙签将两种不同颜色的棉花糖或软糖熊连接在一起。将牙签与糖果仅连接到红色甘草片段或仅与黑色甘草片段连接，以便糖果块在两股之间。握住甘草棒的末端，稍微扭转结构。
新西兰林肯大学生物学 Essay：如何使用糖果制作DNA模型
Gather together red and black licorice sticks, colored marshmallows or gummy bears, toothpicks, needle, string, and scissors. Assign names to the colored marshmallows or gummie bears to represent nucleotide bases. There should be four different colors each representing either adenine, cytosine, guanine or thymine. Assign names to the colored licorice pieces with one color representing the pentose sugar molecule and the other representing the phosphate molecule. Use the scissors to cut the licorice into 1 inch pieces. Using the needle, string half of the licorice pieces together lengthwise alternating between the black and red pieces. Repeat the procedure for the remaining licorice pieces to create a total of two stands of equal length. Connect two different colored marshmallows or gummy bears together using the toothpicks. Connect the toothpicks with the candy to either the red licorice segments only or the black licorice segments only, so that the candy pieces are between the two strands. Holding the ends of the licorice sticks, twist the structure slightly.